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Methotrexate injection protocols have used 50mg m 2 or 75mg intramuscularly or methotrexate tablet protocols use 25mg and 50mg tablets by mouth to terminate pregnancies in patients that are 9 weeks or less gestation.

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Pretreatment and periodic haematological studies are essential to the use of methotrexate in chemotherapy because of its common effect of haematopoietic suppression.

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